Efficacy of ambroxol hydrochloride intravenous injection adjunctive treatment for acute exacerbation of chronic obstructive pulmonary disease

Objective To observe the clinical efficacy of ambroxol hydrochloride injection on acute exacerbation of chronic obstructive pulmonary disease.Methods 80 patients with acute exacerbation of chronic obstructive pulmonary disease in our department from January 2009 to October 2011 were selected.The patients were randomly divided into observation group and control group with 40 cases in each group.Observation group was given conventional therapy plus ambroxol hydrochloride 30 mg intravenous injection twice a day.Control group was only given conventional therapy.The clinical efficacy and arterial blood gas of the two groups were compared after treatment.Results After treatment,the total effective rate of observation group and control group were 95% and 82.5% respectively,there was significant difference between the two groups(P0.05).Compared with control group,arterial blood gas index of the observation group was significantly increased(P0.05).Conclusion Ambroxol hydrochloride intravenous injection adjunctive treatment for acute exacerbation of chronic obstructive pulmonary disease has good efficacy with few side effects,it is safe and reliable.