Efficacy of Ambroxol Hydrochloride Treatment of Chronic Obstructive Pulmonary Disease with Acute Exacerbation

Objective To investigate the ambroxol in the treatment of chronic obstructive pulmonary disease with acute exacerbation of clinical efficacy.Methods Chronic obstructive pulmonary disease with acute exacerbation of 164 cases were randomly divided into control and treatment group,65 patients in control group given routine clinical treatment(oxygen,antibiotics,expectorant,antitussive,antispasmodic asthma,etc.symptomatic and supportive treatment),treatment group,99 patients in the control group on the basis of the treatment given to Ambroxol intravenous infusion therapy,clinical outcomes of two groups for analysis.Results In the control group was 81.54%,the treatment group was 95.96%,a significant difference between two groups was statistically significant(χ2 = 7.60,P0.01),two sets of lung function FVC(L),FEV1(L),FEV1/FVC% a significant improvement compared with before treatment,and the treatment group improved significantly better than the control group significant difference between the two groups was statistically significant(P0.01 or P0.001),two groups were not significant side effects.Conclusion Ambroxol joint anti-infection,cough,symptomatic treatment of chronic obstructive pulmonary disease with acute exacerbation of a significant effect,and safe for clinical application.