The diagnostic value of multiple tumor markers detection protein chip in diagnosis of lung cancer

Objective To assess the value of multi-tumor marker protein biochip detective system in diagnosis of lung cancer. Methods The levels of 12 tumor markers (CA199, NSE, CEA, CA242, CA125, CA153, AFP, Fe, f-PSA, PSA, B-HCG, HGH) in sera of 116 lung cancer patients, 42 patients with benign pulmonary disease and 165 normal persons were determined, analyzed by using multi-tumor markers protein biochip detective system. Results At least one kind of tumor marker was found higher in 88 sera of the 116 lung cancer patients with a positive rate of 75.9%. Seven sera of 42 patients with benign pulmonary disease positive with a positive rate of 16.7%. No tumor markers were observed in 165 normal persons. Conclusion Multi-tumor marker protein biochip detective system possesses clinical reference value in diagnosis of lung caner.