Clinical study of artificial liver treatment on patients with chronic severe hepatitis

Objective To study the therapeutic effects of artificial liver on patients with chronic severe hepatitis. Method Sixty patients with chronic severe hepatitis received a combined therapy artificial liver. Results After artificial liver treatment, serum bilirubin,endotoxin (ET), Tumor necrosis factor alpha (TNFα) in patients with chronic severe hepatitis obviously reduced and prothrombin activity (PTA) increased, symptoms of digestive tract in some patients with chronic severe hepatitis were improved. But it could not reduce Interleukin- 1 bata (IL- 1β)and Interleukin- 6(IL- 6) .The cure and improved rate of these patients was 38.3% by the treatment of artificial liver. This treatment reduced mortality rate of these chronic severe hepatitis patients. Conclusion Artificial liver is an effective therapy for chronic severe hepatitis.