Function Comparison between Siwu Tang and its Three Additional Prescriptions` Medicine on Rats Acute Blood Stasis

Objective Observe and compare Siwu Tang and its additional prescriptions' medicine function on the rat blood stasis model.MethodsChoose 48 Wistar rats and divide into normal group,blood stasis model group,Siwu Tang group,Shengyu Tang group,Taohong Siwu Tang group,Jiaoai Tang group at random,8 rats in per group.Each rat was continuously clystered for 7 days.On the 8th day except normal group,rest 5 rats groups received the subcutaneous injection of Adrenaline Hydrochloride,dose was 0.9 mgs/kg,2 times/d.The rats were ice water soaked as stimulation for 5 mins between 2 injections.Stop food after stimulation.After 18 h,cut the stomach by etherization.Get the blood from abdominal aorta to make examination of hemorheology and the measurement of the clotting time.ResultsCompared with the blood stasis model group, in the rats of group Siwu Tang and Shengyu Tang,the blood viscosity lowered obviously under the shear rate(P0.05 or P0.01 or P≤0.001);In Taohong Siwu group under shear rate 1 s~(-1),blood viscosity lower had very obvious meaning(P0.05).Compared with the blood stasis model group,the rat's Erythrocyte aggregations rate of Taohong Siwu Tang and Jaoai group lowered obviously(P(0.001)).Compared with the group of Siwu Tang,Shengyu Tang group,Taohong Siwu group and Jaoai group's rats' erythrocyte aggreagation index numbers all lowered obviously(P0.05 or P0.01).Among them,in the Taohong Siwu Tang and Jiaoai,the index number rats' Erythrocyte aggregation lowered very obviously(P0.01).Compared with the blood stasis model group,in the set of Siwu Tang,the set of Shengyu Tang Taohong Siwu,rats' H'crit all lowered obviously(P0.05 or P0.01).Compare with the blood stasis model set,the set of Siwu Tang and its additional prescriptions' clotting time all prolonged obviously(P0.01 or P0.01).ConclusionSiwu Tang and its additional prescriptions can all show certain function of promoting blood flow on blood stasis model.The power of the promoting blood flow function has the dissimilarity because of the compatibility.When Siwu Tang and its compatibility work on the promoting blood flow,benefiting vital energy,it has stronger function on promoting blood flows reminding,the effect of prescription is relevant with the status of the object.