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2000•Chinese Journal of New Drugs and Clinical RemediesRequires access

A clinical trial of terbinafine ointment in treatment of superficial mycosis

Wen Zhang

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Abstract

AIM: To evoluate the efficacy and safety of terbinafine ointment in the treatment of superficial mycosis. METHODS: Two hundred and two patients (M 127, F 75; age 36± s 12) with superficial mycosis were treated with terbinafine ointment (given thinly on the suface 2 times daily). The patients with tinea corporis, cruris or versicolor were treated for 1 wk. The patients with tinea manum or pedis of squamus and vesiclar type were treated for 2 wk. The patients with tinea manum or pedis of squamous hyperkeratotic type were treated for 4 wk. RESULTS: The total excellent response rate of terbinafine ointment was 91.1%, clearance rate of fungi was 95.5%. The adverse reaction rate of terbinafine ointment was 2%. CONCLUSION: Terbinafine ointment is a effective and safe drug in treating superficial mycosis.

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AIM: To evoluate the efficacy and safety of terbinafine ointment in the treatment of superficial mycosis. METHODS: Two hundred and two patients (M 127, F 75; age 36± s 12) with superficial mycosis were treated with terbinafine ointment (given thinly on the suface 2 times daily). The patients with tinea corporis, cruris or versicolor were treated for 1 wk. The patients with tinea manum or pedis of squamus and vesiclar type were treated for 2 wk. The patients with tinea manum or pedis of squamous hyperkeratotic type were treated for 4 wk. RESULTS: The total excellent response rate of terbinafine ointment was 91.1%, clearance rate of fungi was 95.5%. The adverse reaction rate of terbinafine ointment was 2%. CONCLUSION: Terbinafine ointment is a effective and safe drug in treating superficial mycosis.

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Available abstract

AIM: To evoluate the efficacy and safety of terbinafine ointment in the treatment of superficial mycosis. METHODS: Two hundred and two patients (M 127, F 75; age 36± s 12) with superficial mycosis were treated with terbinafine ointment (given thinly on the suface 2 times daily). The patients with tinea corporis, cruris or versicolor were treated for 1 wk. The patients with tinea manum or pedis of squamus and vesiclar type were treated for 2 wk. The patients with tinea manum or pedis of squamous hyperkeratotic type were treated for 4 wk. RESULTS: The total excellent response rate of terbinafine ointment was 91.1%, clearance rate of fungi was 95.5%. The adverse reaction rate of terbinafine ointment was 2%. CONCLUSION: Terbinafine ointment is a effective and safe drug in treating superficial mycosis.

Key concepts: Terbinafine, Medicine, Mycosis, Dermatology, Tinea capitis, Adverse effect, Mycosis fungoides, Dermatophyte

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