2009Anhui nongye kexueRequires access

Inhibitory Effects of Composite PSP on HeLa Cells of Human Cervical Cancer

Hao Yan-zhi

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Abstract

[Objective] The aim was to discuss the effect of composite PSP on the proliferation of HeLa cells of human cervical cancer.[Method] PSP and GBE were compounded according to different doses and 3 proportions of 1∶1,1∶2 and 2∶1,and the inhibitory effect of the composite PSP on HeLa cells of human cervical cancer was studied by MTT method.[Result] The inhibitory effects of using PSP and GBE compoundly according to 3 proportions on HeLa cells of human cervical cancer were all obviously better than that of using single component at corresponding doses and the tumor inhibition rate of group at the same proportion showed positive correlation with dose.The combined use of PSP and GBE could produce synergy in inhibiting HeLa cells of human cervical cancer.Among them,the effect of PSP and GBE with the proportion at 2∶1 was most prominent and the tumor inhibition rates at high,middle and low doses were 67.92%,58.93% and 34.86%(P0.01),resp.[Conclusion] The study laid a foundation for curing human cervical cancer.

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[Objective] The aim was to discuss the effect of composite PSP on the proliferation of HeLa cells of human cervical cancer.[Method] PSP and GBE were compounded according to different doses and 3 proportions of 1∶1,1∶2 and 2∶1,and the inhibitory effect of the composite PSP on HeLa cells of human cervical cancer was studied by MTT method.[Result] The inhibitory effects of using PSP and GBE compoundly according to 3 proportions on HeLa cells of human cervical cancer were all obviously better than that of using single component at corresponding doses and the tumor inhibition rate of group at the same proportion showed positive correlation with dose.The combined use of PSP and GBE could produce synergy in inhibiting HeLa cells of human cervical cancer.Among them,the effect of PSP and GBE with the proportion at 2∶1 was most prominent and the tumor inhibition rates at high,middle and low doses were 67.92%,58.93% and 34.86%(P0.01),resp.[Conclusion] The study laid a foundation for curing human cervical cancer.

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Available abstract

[Objective] The aim was to discuss the effect of composite PSP on the proliferation of HeLa cells of human cervical cancer.[Method] PSP and GBE were compounded according to different doses and 3 proportions of 1∶1,1∶2 and 2∶1,and the inhibitory effect of the composite PSP on HeLa cells of human cervical cancer was studied by MTT method.[Result] The inhibitory effects of using PSP and GBE compoundly according to 3 proportions on HeLa cells of human cervical cancer were all obviously better than that of using single component at corresponding doses and the tumor inhibition rate of group at the same proportion showed positive correlation with dose.The combined use of PSP and GBE could produce synergy in inhibiting HeLa cells of human cervical cancer.Among them,the effect of PSP and GBE with the proportion at 2∶1 was most prominent and the tumor inhibition rates at high,middle and low doses were 67.92%,58.93% and 34.86%(P0.01),resp.[Conclusion] The study laid a foundation for curing human cervical cancer.

Key concepts: HeLa, Cervical cancer, Inhibitory postsynaptic potential, MTT assay, Cancer cell, Cancer, Chemistry, Cervical carcinoma

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