The comparative study on the testing results between OYLMPUS AU600 and Dimension Xpand plus automatic biochemistry analyzer

Objective To explore the comparability of the testing results obtained from different biochemistry equipments and clear the possibility of its clinical acceptability.Methods According to the acceptable error in CLSI EP5-A and EP9-A,the precision estimation for the two biochemical equipments were made.The detection system was adopted as the target system(X) which was composed of OYLMPUS AU600 automatic biochemistry analyzer,meanwhile,Dimension Xpand plus automatic biochemistry analyzer was used as evaluated system(Y).Two kinds of control sera(normal and abnormal) were analyzed in eight working days and eighty fresh serum samples were inspected in these days including six biochemical items(BUN,CR,UA,AST,CK,LDH).The relative deviation between the two detection systems was calculated.The comparability of testing results obtained from different equipments was evaluated according to the CLIA′88 standard.Results The systemic errors on most of the results between OYLMPUS AU600 and Dimension Xpand plus were clinically acceptable except individual items including BUN and UA.Conclusions Most of the results tested by two analysis systems are comparable and able to attain the clinical demand,and the reliable results can also be provided by Dimension Xpand plus automatic biochemistry analyzer.