With ALT,AST to Confirm the Different Biochemistry Instrument's Performance

Objective ALT,AST were detected on different analyzer,and their results were analyzed to determine the extent of precision and commeasurability,in order to guarantee the identical laboratory test results.Methods Automatic biochemistry analyzes were performed on the Roche automatic biochemistry analyzes and American Beckmann LX20 referring to NCCLS 《EP9-A》 document requests,to carry on the accuracy,the relevant experiment and experimental technique system error(SE) and the clinical acceptability.Results ALT and AST were operated separately with same mix blood serum on the two instruments for 20 times.The CV value was 3.4~4.6,and the difference was not significant.For two instrument's correlation coefficient,ALT was 0.982 2,AST was 0.9918,R20.975,and the related performance was good.For the experimental technique SE comparison,both ALT and AST medicine decided level 2 and 3,maybe accepted clinically,but their medicine decision level 1 may not be accepted clinically.Conclusion The results of Roche automatic biochemistry analyzer,in each performance inspection,are coincident to the results detected by BackmanLX20 automatic biochemistry analyzer,except partial system error cannot be accepted,no difference was significant.