2004•Zhongguo jiceng yiyaoRequires access

Changes in serum high-sensitivity C-reactive protein and lipoprotein levels in patients with acute coronary syndrome and their responses to atorvastatin

Jun Huang

Abstract

Objective To investigate the levels of Hs-CRP and lipoprotein of ACS patients and the effects of atorvastatin.Methods 69 ACS patients were randomly divided into atorvastatin group(n=40) and routine group(n=29).The serum Hs-CRP and lipoprotein were measured in 69 patients with ACS and 30 controls before and after treatment.Results The serum Hs-CRP levels were significantly higher in the ACS groups than in the control group,closely related to the severity of ACS.After two-week treatment with atorvastatin,the serum Hs-CRP levels were significantly decreased in the atorvastatin groups.Conclusion The serum Hs-CRP levels are closely related to ACS,and the anti-inflammatory effect of atorvastatin plays an important role in the early treatment of ACS.

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Key concepts: Atorvastatin, Medicine, Acute coronary syndrome, C-reactive protein, Internal medicine, Gastroenterology, Lipoprotein, Lipoprotein(a)