Levels of high-sensitivity C-reactive protein,fibrinogen and D-Dimer in serum of patients with coronary heart disease

Objective:To investigate the value of clinical application in coronary heart disease(CHD) by measuring serum levels of high-sensitivity C-reactive protein(hs-CRP),fibrinogen(FIB) and D-Dimer(DD) in patients with CHD.Method:The levels of hs-CRP and D-D in 86 patients with CHD were measured by turbidimetric immunoassay.The level of FIB was detected by Clauss.The 30 healthy cases regarded as controls.Result:①The serum levels of hs-CRP,FIB and D-D in patients with acute myocardial infarction(AMI) and unstable angina(UA) were higher than those in patients with stable angina(SA) and health controls significantly(P0.01).②The serum level of hs-CRP in patients with SA was higher than those in health controls significantly(P0.01).③The serum levels of FIB and D-D were no significant difference between SA and health controls(P0.05).Conclusion:The serum levels of hs-CRP,FIB and D-D can preferably reflect the severe degree of CHD,and have very important clinical value.