Study of the relationship between Lipoprotein(a) and high-sensitivity C-reactive protein and fibrinogen with coronary heart disease

Objective To investigate the relationship between Lipoprotein(a) and High-sensitivity C-reactive Protein(hs-CRP) and Fibrinogen(Fib) with Coronary Heart Disease(CHD).Methods 36 cases of diagnosed CHD patients,were divided into stable angina pectoris group,unstable angina pectoris group and acute myocardial infarction group.The fasting blood of all patients were used to detect the level of Lp(a),hs-CRP,Fib.12 healthy persons were as controls.Results Lp(a),hs-CRP,Fib level in each CHD group compared with normal control group were significantly elevated,each index in acute myocardial infarction and unstable angina group than that in stable angina group were significantly higher.Conclusion The level of Lp(a),hs-CRP and Fib has a close relationship with CHD,which has important clinical significance to observe the severity and evolution of CHD.