Analysis of Antibiotic Resistance in 954 Strains of Bacteria Isolated fromBurn Wounds during 1998-2000

Objective To survey the changes in antibiotic resistance of bacteria isolated from burn wounds. Methods Diffusion tests were used to measure the antibiotic sensitivity of bacteria isolated from burn wounds. Results The positive rate of S. aureus in the culture of 954 strains of bacteria occupied the first position(27. 5% ). The second was P. aeruginosia( 19. 5% ) to be followed by S. epidermidis, entero-coccus faecalis, klebsiella pneumoiae and enterobacter cloacae (10.4% , 6.8% , 4. 1% and 2.6% , respec-tirely). S. aureus was 100% sensitive to vancomycin. Resistance of P. aeruginosa to the third generation cephalosporins and imipenem increased significantly. The resistance percentage of amikacin to the most isolates with exception to P. aeruginosa reduced in varying degrees. Conclusion It is important to survey periodically the changes of antibiotic resistance. The rational application of antibiotic is the key measure for controlling and delaying antibiotic resistance.