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2011•Science and Technology of Food IndustryRequires access

Study on evaluation of antioxidant activity of Noni juice in vivo

Rui Long

Open publisher page 9 citations

Abstract

Objective:To research the anti-oxidative activity of Noni juice in aged mice.Method:Tahitian Noni juice(TNJ)was administrated by gavage[5,10,30mL/(kg·bw)] to male mice(10-month-old CL ICR)for 30d.The mice were then sacrificed,and the blood and the livers were collected.The concentration of malondialdehyde(MDA)in the blood and the level of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in the liver were then measured by spectrophotometry.Result:TNJ produced a dose-dependent decrease of MDA,at the same time a dose-dependent increase of SOD and GSH-Px at all three doses.Conclusion:TNJ had antioxidant activity by protecting body against free radical-induced damage.

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What this paper is about

Objective:To research the anti-oxidative activity of Noni juice in aged mice.Method:Tahitian Noni juice(TNJ)was administrated by gavage[5,10,30mL/(kg·bw)] to male mice(10-month-old CL ICR)for 30d.The mice were then sacrificed,and the blood and the livers were collected.The concentration of malondialdehyde(MDA)in the blood and the level of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in the liver were then measured by spectrophotometry.Result:TNJ produced a dose-dependent decrease of MDA,at the same time a dose-dependent increase of SOD and GSH-Px at all three doses.Conclusion:TNJ had antioxidant activity by protecting body against free radical-induced damage.

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Available abstract

Objective:To research the anti-oxidative activity of Noni juice in aged mice.Method:Tahitian Noni juice(TNJ)was administrated by gavage[5,10,30mL/(kg·bw)] to male mice(10-month-old CL ICR)for 30d.The mice were then sacrificed,and the blood and the livers were collected.The concentration of malondialdehyde(MDA)in the blood and the level of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in the liver were then measured by spectrophotometry.Result:TNJ produced a dose-dependent decrease of MDA,at the same time a dose-dependent increase of SOD and GSH-Px at all three doses.Conclusion:TNJ had antioxidant activity by protecting body against free radical-induced damage.

Key concepts: Malondialdehyde, Superoxide dismutase, Antioxidant, Glutathione peroxidase, Chemistry, In vivo, Glutathione, Food science

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