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ANTIOXIDANT EFFECT OF HAWTHORN EXTRACT ON D-GALACTOSE INDUCED AGING MICE MODLE

Hui Ye

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Abstract

To study the antioxidant effect of the hawthorn extract on D-galactose induced aging mice model. This paper has chosen Babl/C mice as the object. While the mice were injected with D-galactose, they were also treated with hawthorn extract in low, medium and high doses respectively through oral gavage. The activi ties of superoxide dismutase (SOD) in blood serum and SOD, glutathione peroxidase (GSH-Px) and catalase (CAT) in liver were determined after six weeks. In medium and high doses groups, the levels of SOD in blood serum and CAT in liver showed significantly higher than those in D-galactose induced aging mice group (p0.01). The activities of SOD and GSH-Px in liver increased compared with the levels of model group (p0.05).

About this research paper

What this paper is about

To study the antioxidant effect of the hawthorn extract on D-galactose induced aging mice model. This paper has chosen Babl/C mice as the object. While the mice were injected with D-galactose, they were also treated with hawthorn extract in low, medium and high doses respectively through oral gavage. The activi ties of superoxide dismutase (SOD) in blood serum and SOD, glutathione peroxidase (GSH-Px) and catalase (CAT) in liver were determined after six weeks. In medium and high doses groups, the levels of SOD in blood serum and CAT in liver showed significantly higher than those in D-galactose induced aging mice group (p0.01). The activities of SOD and GSH-Px in liver increased compared with the levels of model group (p0.05).

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Available abstract

To study the antioxidant effect of the hawthorn extract on D-galactose induced aging mice model. This paper has chosen Babl/C mice as the object. While the mice were injected with D-galactose, they were also treated with hawthorn extract in low, medium and high doses respectively through oral gavage. The activi ties of superoxide dismutase (SOD) in blood serum and SOD, glutathione peroxidase (GSH-Px) and catalase (CAT) in liver were determined after six weeks. In medium and high doses groups, the levels of SOD in blood serum and CAT in liver showed significantly higher than those in D-galactose induced aging mice group (p0.01). The activities of SOD and GSH-Px in liver increased compared with the levels of model group (p0.05).

Key concepts: Superoxide dismutase, Catalase, Antioxidant, Glutathione peroxidase, Galactose, Chemistry, Glutathione, Biochemistry

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ANTIOXIDANT EFFECT OF HAWTHORN EXTRACT ON D-GALACTOSE INDUCED AGING MICE MODLE — Research Paper | ScholarLens