Comparison of clinical efficacy of imipenem and cefoperazone sulbactam in treatment of spontaneous bacterial peritonitis of liver cirrhosis

Objective To compare the curative effect of imipenem and cefoperazone sulbactam in treatment of spontaneous bacterial peritonitis of liver cirrhosis. Methods Seventy patients with spontaneous bacterial peritonitis of liver cirrhosis were divided into imipenem group(A group,35 cases) and cefoperazone sulbactam group(B group,35 cases).A group was treated with abdominal puncture combined with imipenem,and B group was treated with abdominal puncture combined with cefoperazone sulbactam.The cure time of two groups was 10 days.The treatment effects,the changes of clinical symptoms were observed after treatment. Results The total effective rate of A group(82.9%) was significantly better than that of B group(68.6%)(P0.05).The remission time of clinical symptoms in A group after treatment was earlier than that of B group(P0.05). Conclusion The treatment of imipenem for spontaneous bacterial peritonitis of liver cirrhosis has a good effect.It could alleviate the clinical symptoms and be worthy of clinical application.