Effect and Nursing Cooperation of Dexmedetomidine on Laparoscopic Hysterectomy Patients at the Recovery Period

Objective To determine the effect and nursing cooperation of dexmedetomidine on laparoscopic hysterectomy patients at the recovery period in general anesthesia. Methods 40 patients with laparoscopic hysterectomy were randomly divided into dexmedetomidine group(group D) or control group(group C). At 30 minutes before induction of anesthesia, patients in group D were administered dexmedetomidine at a dose of 1 μg/kg over 10 min and in group C patients were given a placebo infusion of normal saline at identical rates.The two groups were given to endotracheal intubation, inhalation anesthesia. Patients in group D were administered dexmedetomidine at a dose of 0.3 μg·kg·h-1 in the maintenance of anesthesia and in group C patients were given a placebo infusion of normal saline. The extubation time and OAA/S score and agitation rate after extubation 15 min were recorded. Results OAA/S score and agitation rate in group D during periextubation were significantly different from those in group C (P 0.05). Conclusion Dexmedetomidine can not affect the extubation time and effectively reduce the restlessness complications to extubation in patients with laparoscopic hysterectomy and nursing risk.