Diagnostic value of serum cTnl,CK-MB mass and hs-CRP in children patients with viral myocarditis

Objective To evaluate the diagnostic value of co-detecting serum levels of cTnI,CK-MB mass and hsCRP in children with viral myocarditis(VMC).Methods All 67 eases of VMC,72 cases of suspected myocarditis(NVMC) and 65 cases of healthy control children were included.Serum levels of cTnI,CK-MB mass and hs-CRP were detected in all the children.Results The serum levels of cTnI,CK-MB mass and hs-CRP in VMC group were much higher than those in NVMC groups(P 0.01).The sensitivity of single index of cTnl,CK-MB mass and hs-CRP in diagnosis of VMC was hsCRP (68.66%) cTnI(65.67%) CK-MB mass(55.22%),and the specificity was cTnI(100.00%) CK-MB mass (93.06%) hs-CRP(81.94%).The diagnosis specificity of combined determination of the three parameters for VMC (92.09%) was higher than the single index of cTnI,CK-MB mass and hs-CRP.The dynamic detection of the three indicators in children with VMC indicated that during the rehabilitation of the patients,hs-CRP recovered fastest,CK-MB recovered the second fastest,cTnI recovered most slowly.Conclusion Co-detection of serum levels of cTnI,CK-MB mass and hs-CRP is more specific than the single index and it may enhance the accuracy of diagnosis for VMC.