Value of joint detection of cTnI,CK-MB mass and hs-CRP in pediatric VMC
Zhong Bin-ca
Abstract
Zhong Bin-ca
Abstract
Objective:To investigate the joint detection of cTnI,CK-MB mass and hs-CRP in pediatric viral myocarditis(VMC).Methods:All patients were divided into three groups:Viral myocarditis group(VMC,n=60),suspected viral myocarditis group(NVMC,n=57)and healthy control group(n=62).Five mL of venous blood was extracted,the serum levels of cTnI,CK-MB mass and hs-CRP were determined.Results:In VMC group hs CRP,CK-MB mass and cTnI levels were significantly higher than those of NVMC group and control group(P0.05).hs-CRP in serum disappeared quickly,and existence time of cTnI was the longest.hs-CRP showed the highest sensitivity(75.0%)and cTnI showed best specificity(89.4%).The sensitivity of combination detection was 93.3%,specificity was 96.5%and the accuracy was 94.9%.Conclusion:Joint detection of cTnI,CK-MB mass and hs-CRP is accurate in diagnosis the pediatric viral myocarditis.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective:To investigate the joint detection of cTnI,CK-MB mass and hs-CRP in pediatric viral myocarditis(VMC).Methods:All patients were divided into three groups:Viral myocarditis group(VMC,n=60),suspected viral myocarditis group(NVMC,n=57)and healthy control group(n=62).Five mL of venous blood was extracted,the serum levels of cTnI,CK-MB mass and hs-CRP were determined.Results:In VMC group hs CRP,CK-MB mass and cTnI levels were significantly higher than those of NVMC group and control group(P0.05).hs-CRP in serum disappeared quickly,and existence time of cTnI was the longest.hs-CRP showed the highest sensitivity(75.0%)and cTnI showed best specificity(89.4%).The sensitivity of combination detection was 93.3%,specificity was 96.5%and the accuracy was 94.9%.Conclusion:Joint detection of cTnI,CK-MB mass and hs-CRP is accurate in diagnosis the pediatric viral myocarditis.
Key concepts: Medicine, Troponin I, Viral Myocarditis, Internal medicine, Myocarditis, Cardiology, Gastroenterology, C-reactive protein