2010•Kunming Yike Daxue xuebaoRequires access
Analgesic and Anti-inflammatory Effects of Dudong Capsule
Guang Liu
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Abstract
Objective To investigate the analgesic and anti-inflammatory effects of Dudong capsule,and to provide more detailed experimental bases for clinic application.Methods Method of twisting response caused by acetic acid and hot plate method were used to evaluate the analgesic effects.Anti-inflammatory effects were determined by models including auricle tumefaction induced by dimethylbenzene in mice and paw edema induced by carrageenin in rats.Results Dudong capsule at high and medium dosage obviously decreased the frequency of writhe caused by acetic acid in mice and delayed the pain reaction time of heat stimulation in mice.Dudong capsule at high dosage also had markedly inhibitory effect on dimethylbenzene-induced auricle tumefaction in mice and mitigated the degree of paw edema induced by carrageenin in rats.Conclusion Dudong capsule has evident anti-inflammatory and analgesic effects.