The Levels of Cerebrospinal Fluid and Serum IL-2、IL-7 and NSE in Children with Simple and Complex Febrile Seizures

Objective To evaluate the relationships of brain injury after febrile seizures and the levels of serum IL-2、IL-7 and NSE in children with simple and complex febrile convulsion from the changes of IL-2、IL-7 and NSE.Methods Twenty-two cases of simple FS,nineteen cases of complex FS and twenty cases of children with fever but without convulsions were selected in this study.Children with fever but without convulsions were control group.Children's cerebrospinal fluid and serum IL-2、IL-7 and NSE were measured by ELISA.Results The levels of cerebrospinal fluid IL-2 and IL-7 in children with simple and complex febrile convulsion was significantly higher than those in control group.The difference was significant(P0.01).The levels of cerebrospinal fluid IL-2 and IL-7 in children with simple febrile convulsion was significantly higher than complex febrile convulsion.The difference was significant(P0.01).Conclusion The levels of IL-2、IL-7 and NSE in children had the relationship with the degree of brain injury.