Relationship of Serum Neuron-Specific Enolase and Brain Damage in Children with Febrile Seizures

Objective To evaluate the brain damage of patients with febrile seizures by measuring serum neuron-specific enolase((S-NSE).)Methods Blood samples were collected from 49 febrile seizures patients including 32 cases of simple febrile seizures,17 cases of complex febrile seizures and 23 fever patients as control group,the S-NSE was measured by enzyme immunoassay(EIA).Results The S-NSE levels of patients with simple febrile seizures were(5.17±1.31) μg/L;The S-NSE levels of patients with complex febrile seizures were(5.84±1.62) μg/L.There were no significant differences in febrile seizures group and control group(P0.05).Conclusion Febrile seizures seldomly cause severe neurological damage.