2013Laboratory Medicine and ClinicRequires access

Clinical distribution and drug resistance analysis of Acinetobacter baumannii

Xiaoli Zhang

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Abstract

Objective To investigate clinical distribution and drug resistance of Acinetobacter baumannii in The First Hospital Affiliated to Jiamusi University.Methods Bacteria culture and identification were adopted by conventional method.Kirby-bauer method was used as drug sensitive test.Results Acinetobacter baumannii in sputum specimens up to 62.0%(98/158),followed by pus and secretion samples of 14.6%(23/158);Acinetobacter baumannii for nosocomial infection,in the department of respiratory,Acinetobacter baumannii distribution for a maximum of 33.5%(53/158),followed by the departments of neurology,intensive care unit,burns deparbment.In 18 kinds of antibacterials,the resistance rate of imipenem in carbapenems was the lowest(17.1%),the resistant rute of meropenem was 21.5%,other antimicrobial resistance rates were higher than 40.0%.Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in nosocomial infection,and drug resistance rate is higher.Clinicians should rationally choose antibacterials according to susceptibility test results,regular resistance test,in order to effectively control the infection,reduce the resistant strains of Acinetobacter baumannii.

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Objective To investigate clinical distribution and drug resistance of Acinetobacter baumannii in The First Hospital Affiliated to Jiamusi University.Methods Bacteria culture and identification were adopted by conventional method.Kirby-bauer method was used as drug sensitive test.Results Acinetobacter baumannii in sputum specimens up to 62.0%(98/158),followed by pus and secretion samples of 14.6%(23/158);Acinetobacter baumannii for nosocomial infection,in the department of respiratory,Acinetobacter baumannii distribution for a maximum of 33.5%(53/158),followed by the departments of neurology,intensive care unit,burns deparbment.In 18 kinds of antibacterials,the resistance rate of imipenem in carbapenems was the lowest(17.1%),the resistant rute of meropenem was 21.5%,other antimicrobial resistance rates were higher than 40.0%.Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in nosocomial infection,and drug resistance rate is higher.Clinicians should rationally choose antibacterials according to susceptibility test results,regular resistance test,in order to effectively control the infection,reduce the resistant strains of Acinetobacter baumannii.

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Available abstract

Objective To investigate clinical distribution and drug resistance of Acinetobacter baumannii in The First Hospital Affiliated to Jiamusi University.Methods Bacteria culture and identification were adopted by conventional method.Kirby-bauer method was used as drug sensitive test.Results Acinetobacter baumannii in sputum specimens up to 62.0%(98/158),followed by pus and secretion samples of 14.6%(23/158);Acinetobacter baumannii for nosocomial infection,in the department of respiratory,Acinetobacter baumannii distribution for a maximum of 33.5%(53/158),followed by the departments of neurology,intensive care unit,burns deparbment.In 18 kinds of antibacterials,the resistance rate of imipenem in carbapenems was the lowest(17.1%),the resistant rute of meropenem was 21.5%,other antimicrobial resistance rates were higher than 40.0%.Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in nosocomial infection,and drug resistance rate is higher.Clinicians should rationally choose antibacterials according to susceptibility test results,regular resistance test,in order to effectively control the infection,reduce the resistant strains of Acinetobacter baumannii.

Key concepts: Acinetobacter baumannii, Meropenem, Imipenem, Drug resistance, Microbiology, Acinetobacter, Medicine, Antibiotic resistance

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