Clinical Distribution and Drug Resistance of Acinetobacter baumannii Isolates

Objective To study the distribution and drug resistance of Acinetobacter baumannii,and to offer reasonable experimental data for clinical therapeutics.Methods A total of 259 Acinetobacter baumannii isolates were retrospectively analyzed according to specimen source,infection in different departments and drug-resistance.Results Among the 259 strains,209(80.7%)came from sputum specimens.Acinetobacter baumannii strains were mainly distributed in the ICUs,respiratory department,neurology department,and etc.The drug susceptibility reports showed that the bacterial resistance rate to common antimicrobial agents increased annually.Meropenem had the strongest activity against Acinetobacter baumannii,followed by levofloxacin and tobramycin.High resistance rate in ampicillin,nitrofurantoin and mezlocillin(73.5%)was presented.The strains displayed multi-drug resistance as well.Conclusions The rate of nosocomial infections caused by Acinetobacter baumannii increases year after year,moreover Acinetobacter baumannii strains show multi-drug resistance.For improving the curative effect and delaying the occurrence of bacteria resistance,it is important to strengthen the clinical monitoring and rationally use antibiotics.