2010Medical Journal of Chinese People's HealthRequires access

Analysis of infection distribution and drug resistance of Acinetobacter Baumannii

Wang Yue-ni

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Abstract

Objective:To investigate the clinical distribution and drug resistance of Acinetobacter baumannii in order to offer basis for the clinical therapeutics.Methods:Analyze the infection distribution and drug resistance of 71 samples of Acinetobacter baumannii that were isolated from various kinds of specimens from inpatients.The drug sensitivity test was done by means of dilution,and then the results were assessed with CLSI(Clinical and Laboratory Standards Institute).Results: Acinetobacter baumannii samples were mainly distributed in ICU ward,Brain Surgery department and Respiration department.The highest positive rate of Acinetobacter baumannii was in sputum(95.77%).The resistance rates to Imipenem(31.0%) were the lowest,and to Cefoperazone-Sulbactam(39.4%) came to be next.Acinetobacter baumannii were high resistant to other 20 tested antibiotics.Conclusions: Acinetobacter baumannii is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents.Consequently,clinical doctors should attach more importance to the infection resulted from Acinetobacter Baumannii,pay more attention to inpatients easily infected,monitor it more frequently,and use antibiotics more carefully in order to increase the positive effect and reduce drug resistance.

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Objective:To investigate the clinical distribution and drug resistance of Acinetobacter baumannii in order to offer basis for the clinical therapeutics.Methods:Analyze the infection distribution and drug resistance of 71 samples of Acinetobacter baumannii that were isolated from various kinds of specimens from inpatients.The drug sensitivity test was done by means of dilution,and then the results were assessed with CLSI(Clinical and Laboratory Standards Institute).Results: Acinetobacter baumannii samples were mainly distributed in ICU ward,Brain Surgery department and Respiration department.The highest positive rate of Acinetobacter baumannii was in sputum(95.77%).The resistance rates to Imipenem(31.0%) were the lowest,and to Cefoperazone-Sulbactam(39.4%) came to be next.Acinetobacter baumannii were high resistant to other 20 tested antibiotics.Conclusions: Acinetobacter baumannii is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents.Consequently,clinical doctors should attach more importance to the infection resulted from Acinetobacter Baumannii,pay more attention to inpatients easily infected,monitor it more frequently,and use antibiotics more carefully in order to increase the positive effect and reduce drug resistance.

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Available abstract

Objective:To investigate the clinical distribution and drug resistance of Acinetobacter baumannii in order to offer basis for the clinical therapeutics.Methods:Analyze the infection distribution and drug resistance of 71 samples of Acinetobacter baumannii that were isolated from various kinds of specimens from inpatients.The drug sensitivity test was done by means of dilution,and then the results were assessed with CLSI(Clinical and Laboratory Standards Institute).Results: Acinetobacter baumannii samples were mainly distributed in ICU ward,Brain Surgery department and Respiration department.The highest positive rate of Acinetobacter baumannii was in sputum(95.77%).The resistance rates to Imipenem(31.0%) were the lowest,and to Cefoperazone-Sulbactam(39.4%) came to be next.Acinetobacter baumannii were high resistant to other 20 tested antibiotics.Conclusions: Acinetobacter baumannii is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents.Consequently,clinical doctors should attach more importance to the infection resulted from Acinetobacter Baumannii,pay more attention to inpatients easily infected,monitor it more frequently,and use antibiotics more carefully in order to increase the positive effect and reduce drug resistance.

Key concepts: Acinetobacter baumannii, Cefoperazone, Drug resistance, Sulbactam, Imipenem, Medicine, Acinetobacter, Microbiology

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