Investigation of pseudomonas aeruginosa infection and drug resistance

OBJECTIVE To investigate the infection status and drug-resistance of Pseudomonas aeruginosa(PAE) in nosocomial infections to provide the scientific according to the clinical application of the antibiotics.METHODS PAE were cultured and identified according to the National Clinical Laboratory Operation Rules.The drug sensitivity testing was performed by K-B methods.RESULTS Totally 219 strains of PAE were mainly isolated from the intensive care unit(31.1%),department of internal medicine(24.7%),department of surgery(18.7%) and department of tumor(17.3%).Most of the ABA strains were detected from sputum,pus and secretions,urine,chest ascites and blood,accounting for 31.1%,24.7%,18.7% and 17.3%,respectively.Drug resistance rates of PAE were higher to 14 kinds of antibiotics were,including SMZ/TMP,gentamycin,cefotaxime,cefepime,aztreonam,ciprofloxacin,levofloxacin and so on,arriving at 45.2%-84.9%.CONCLUSION Drug resistance status of PAE is serious.Hospital should strengthen the monitoring,prevention and controlling of it.