Clinical observation of Montelukast and Glucocorticoid in children with cough variation asthma

Objective To investigate the curative effect of combing montelukast with inhaled corticosteroids in treatment of children with CVA.Methods All the 67 examples diagnosed CVA were divided into the treatment group(n=34) and the control group(n=33) randomly.The children in treatment group were treated with montelukast Combined with inhaled Glucocorticoid,while those in the control group were treated only with inhaled Glucocorticoid.Observations were made on clinical therapeutic effects,the peak expiratory flow rate(PEFR) and the recurrence.Results Clinical efficacy the respiratory peak flow velocity(PEF),and the recurrence rate were better in the treatment group than in the control group,and the difference between the two groups had statistical significance(P 0.05).Conclusion Montelukast combined with Glucocorticoid in the treatment of childhood with cough variant asthma can boost clinical efficiency greatly,and reduce the recurrence.It′s worth to be promoted and applied widely in clinical practice.