The Recent Advances in the Treatment of Gastroesophageal Reflux Disease

Gastroesophageal reflux disease(gastroesophaeal reflux diseases, GERD) is one of the most common disease in medical practice, there is an upward trend in the incidence of a disease throughout the world, and increases with age, 40-60 years for high-risk age[1]. GERD is a caused by the stomach, duodenum content into esophageal symptoms and(or) complications of the disease, GERD in clinic can be roughly divided into: erosive esophagitis(EE)(reflux esophagitis(RE) and non erosive esophagitis(NERD). See the largest NERD, accounts for about 60%. GERD forward less damaging, but it was a long and easy to relapse, seriously affected the quality of life. Mainly for esophageal symptoms(including typical heartburn and reflux) and extraesophageal symptoms(including pharyngeal foreign body sensation, cough, hoarseness, sore throat, asthma, etc.), and increase the development of Barrett's esophagus and esophageal cancer risk[2,3]. Aim of treatment for GERD is healing esophagitis, quickly relieve symptoms, reduce the recurrence, improve the quality of life, treatment method mainly includes the following four aspects: general treatment, drug therapy, endoscopic treatment and surgical treatment. In recent years has become a hot research at home and abroad, this paper summarize the progress in treatment of GERD.