ScholarLens Back to search
2007•Unpublished venueRequires access

Study On Protective Efficacy of HBIG Combining With HBsAg Vaccine in Blocking Mother-Infant Transmission of Hepatitis B Virus

Maolin Chen

Open publisher page 0 citations

Abstract

Objective This study was to investigate the preventive efficacy of HBIG combining with HBsAg Vaccine in Bloking Mother-Infant Transmission of Hepatitis B Virus; Methods 225 infants, whose mother with hepatitis B surface antigen (HBsAg) carrier, were divided into 2 group, HBvac 30ug was given at 0,1,6 month in control group, while at pregnancy and birth combining with HBIG 200IU in caring group, serum HBsAg was followed up for one year. Results chronicity of HBsAg in children with HBsAg positive at birth decreased And the incidence of chronic HBSAg infection deceased from 12.7% to 4.06%, compared to caring group in I year(P0.05). Conclusions combing therapy of HBIG and HBvac may interrupt maternal-infantive transmission and decrease the chronic HBSAg infection. It should be pay close attention to whole society.

About this research paper

What this paper is about

Objective This study was to investigate the preventive efficacy of HBIG combining with HBsAg Vaccine in Bloking Mother-Infant Transmission of Hepatitis B Virus; Methods 225 infants, whose mother with hepatitis B surface antigen (HBsAg) carrier, were divided into 2 group, HBvac 30ug was given at 0,1,6 month in control group, while at pregnancy and birth combining with HBIG 200IU in caring group, serum HBsAg was followed up for one year. Results chronicity of HBsAg in children with HBsAg positive at birth decreased And the incidence of chronic HBSAg infection deceased from 12.7% to 4.06%, compared to caring group in I year(P0.05). Conclusions combing therapy of HBIG and HBvac may interrupt maternal-infantive transmission and decrease the chronic HBSAg infection. It should be pay close attention to whole society.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective This study was to investigate the preventive efficacy of HBIG combining with HBsAg Vaccine in Bloking Mother-Infant Transmission of Hepatitis B Virus; Methods 225 infants, whose mother with hepatitis B surface antigen (HBsAg) carrier, were divided into 2 group, HBvac 30ug was given at 0,1,6 month in control group, while at pregnancy and birth combining with HBIG 200IU in caring group, serum HBsAg was followed up for one year. Results chronicity of HBsAg in children with HBsAg positive at birth decreased And the incidence of chronic HBSAg infection deceased from 12.7% to 4.06%, compared to caring group in I year(P0.05). Conclusions combing therapy of HBIG and HBvac may interrupt maternal-infantive transmission and decrease the chronic HBSAg infection. It should be pay close attention to whole society.

Key concepts: Medicine, HBsAg, Transmission (telecommunications), Pregnancy, Hepatitis B virus, Virology, Incidence (geometry), Immunology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Study On Protective Efficacy of HBIG Combining With HBsAg Vaccine in Blocking Mother-Infant Transmission of Hepatitis B Virus — Research Paper | ScholarLens