Relationship of C-reactive protein,fibrinogen and carotid atherosclerosis in ischemic stroke patients.

Objective To evaluate the relationship of high sensitive C-reactive protein (hs-CRP),fibrinogen and carotid atherosclerosis in ischemic stroke patients.Methods The ischemic stroke patients underwent ecocolordoppler examination to detect the intima-media thickness (IMT) and the plaque formation of the common carotid arteries.A blood sample was drawn to evaluate the concentration of hs-CRP and fibrinogen.Results 125 ischemic stroke patients were included.There were 40 patients with carotid atherosclerosis disorders,16 of whom were diagonosed with carotid atherosclerosis plaque and 24 with increased IMT.The average levels of fibrinogen and hs-CRP were significantly higher in patients with carotid atherosclerosis disorders than those without carotid atherosclerosis disorders (P0.05 and P0.01).The increase in the incidence of carotid atherosclerosis was associated with the increase in the levels of fibrinogen and hs-CRP.Conclusion The high plasma levels of hs-CRP and fibrinogen are strongly associated with carotid atherosclerosis in patients with ischemic stroke inpatients.