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Research on comparison of different extraction process of Radix Codonopsis

Jun Shi

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Abstract

Objective To establish the extraction method of Radix Codonopsis by comparing the different extraction processes.Methods The merceration,methanol reflux,Soxhlet extractor reflux and ultrasonic extraction were compared,and the concentration of Lobetyolin was determined by HPLC.Results The concentrations of lobetyolin by four extraction methods were 0.507,1.013,0.929 and 0.733 mg·g-1,respectively.Conclusion Methanol reflux was the optimal extraction process of Radix Codonopsis,which was simple and stable.

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Objective To establish the extraction method of Radix Codonopsis by comparing the different extraction processes.Methods The merceration,methanol reflux,Soxhlet extractor reflux and ultrasonic extraction were compared,and the concentration of Lobetyolin was determined by HPLC.Results The concentrations of lobetyolin by four extraction methods were 0.507,1.013,0.929 and 0.733 mg·g-1,respectively.Conclusion Methanol reflux was the optimal extraction process of Radix Codonopsis,which was simple and stable.

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Available abstract

Objective To establish the extraction method of Radix Codonopsis by comparing the different extraction processes.Methods The merceration,methanol reflux,Soxhlet extractor reflux and ultrasonic extraction were compared,and the concentration of Lobetyolin was determined by HPLC.Results The concentrations of lobetyolin by four extraction methods were 0.507,1.013,0.929 and 0.733 mg·g-1,respectively.Conclusion Methanol reflux was the optimal extraction process of Radix Codonopsis,which was simple and stable.

Key concepts: Codonopsis, Radix (gastropod), Chromatography, Extraction (chemistry), Extractor, Methanol, Chemistry, High-performance liquid chromatography

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