204 Isolation and Identification of Streptococcus Pneumoniae Resistance

Objective Understanding of the Court and the drug resistance of Streptococcus pneumoniae distribution in the fourth people's hospital of Zigong.Methods The fourth people's hospital of Zigong in July 2006 to 2009 in June from 204 clinical isolates of Streptococcus pneumoniae by K-B disk diffusion assay of penicillin and other antibiotics,the sensitivity of 8,with E-test method detection of methicillin-resistant drug penicillin MIC values of Streptococcus pneumoniae.Results Penicillin resistance is rising,particularly in July 2008-2 009 years in June.Streptococcus pneumoniae to tetracycline,erythromycin,clindamycin has high resistance rate of 83.3%,89.2%,90.2%;resistance to penicillin was 52.5%,cefotaxime resistance 15.7%;chloramphenicol,of loxacin resistance rates were 23.5%,5.4%,no vancomycin resistant strains.Penicillin-insensitive Streptococcus pneumoniae(PNSSP) of the E-test results to intermediate strain-based,PNSSP the MIC values of up to 6μg/mL.Conclusion Resistant Streptococcus pneumoniae isolated hospital more serious in the fourth people's hospital of Zigong,penicillin-resistant Streptococcus pneumoniae rising and it is necessary for drug resistance surveillance to guide clinical selection of antibiotics.