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2011•China Modern MedicineRequires access

Treatment with atorvastatin carotid atherosclerosis in patients with clinical observation of high blood cholesterol

Guiping Li

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Abstract

Objective:To observation the efficacy of atorvastatin in the treatment of hyperdipidemia in the patients with carotid artery atheroselerotic plaques.Methods:88 cases with hypedipidemia were given atorvastatin 20 mg/d before sleeping in the evening for 16 weeks.Before and after the treatment,the change of IMT,TC,TG,LDL-C,(TC-HDL-C)/HDL-C,Lp(a),HDL-C,hemorheology index was examined and compared.The difference was significant (P0.05).Results:After 24 weeks of treament atorvastatin can IMT after treatment (0.68±0.18) mm compared before treatment (1.26±0.02) mm,P0.05,and it could decrease TC,LDL-C,TG,(TC—HDL-C) /HDL-C,Lp(a),increase HDL-C and ameliorate hemorheology index significantly.Conclusion:These suggest that atorvastatin may stabilize the carotid artery atheroselerotic plaques and decrease blood lipid.The side reactions is mild and relatively rare.

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What this paper is about

Objective:To observation the efficacy of atorvastatin in the treatment of hyperdipidemia in the patients with carotid artery atheroselerotic plaques.Methods:88 cases with hypedipidemia were given atorvastatin 20 mg/d before sleeping in the evening for 16 weeks.Before and after the treatment,the change of IMT,TC,TG,LDL-C,(TC-HDL-C)/HDL-C,Lp(a),HDL-C,hemorheology index was examined and compared.The difference was significant (P0.05).Results:After 24 weeks of treament atorvastatin can IMT after treatment (0.68±0.18) mm compared before treatment (1.26±0.02) mm,P0.05,and it could decrease TC,LDL-C,TG,(TC—HDL-C) /HDL-C,Lp(a),increase HDL-C and ameliorate hemorheology index significantly.Conclusion:These suggest that atorvastatin may stabilize the carotid artery atheroselerotic plaques and decrease blood lipid.The side reactions is mild and relatively rare.

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Available abstract

Objective:To observation the efficacy of atorvastatin in the treatment of hyperdipidemia in the patients with carotid artery atheroselerotic plaques.Methods:88 cases with hypedipidemia were given atorvastatin 20 mg/d before sleeping in the evening for 16 weeks.Before and after the treatment,the change of IMT,TC,TG,LDL-C,(TC-HDL-C)/HDL-C,Lp(a),HDL-C,hemorheology index was examined and compared.The difference was significant (P0.05).Results:After 24 weeks of treament atorvastatin can IMT after treatment (0.68±0.18) mm compared before treatment (1.26±0.02) mm,P0.05,and it could decrease TC,LDL-C,TG,(TC—HDL-C) /HDL-C,Lp(a),increase HDL-C and ameliorate hemorheology index significantly.Conclusion:These suggest that atorvastatin may stabilize the carotid artery atheroselerotic plaques and decrease blood lipid.The side reactions is mild and relatively rare.

Key concepts: Atorvastatin, Medicine, Hemorheology, Internal medicine, Carotid arteries, Evening, Blood lipids, Cardiology

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Treatment with atorvastatin carotid atherosclerosis in patients with clinical observation of high blood cholesterol — Research Paper | ScholarLens