The influence of sevofluen anesthesia in elderly patients with cancer of cognitive function after surgery for clinical anesthesia

Objective Observation of sevoflurane anesthesia in elderly patients with cancer of cognitive function after surgery for clinical anesthesia and narcotic drugs selected to provide reference.Method Select February 2008-February 2010 in our hospital 126 cases of elderly patients with tumors were randomly divided into control group and observation group of 63 cases.The control group after induction of anesthesia in patients with TCI 2-4 μg/ml and anesthesia was maintained with propofole,and the observation group after induction of anesthesia in patients given 1.0 to 3.0% inhaled sevoflurane to maintain anesthesia.Depth of anesthesia to maintain dual-band EEG index(BIS)45~55;blood pressure,heart rate control in the basic value within 20%.Observed in patients during anesthesia,before anesthesia,after answering 1 h,3 h,6 h,24 h using Mini Mental State Examination(MMSE)evaluated cognitive function in patients.Result After answering the two groups were 1 h,3 h when the MMSE score significantly lower than that before anesthesia,the difference was statistically significant(P0.05);the control group after 6 h,response in patients with MMSE scores and MMSE scores before anesthesia,the difference was not statistically significant(P0.05);The patients response after 6 h,MMSE scores were significantly lower MMSE scores before anesthesia,the difference was statistically significant(P0.05);two groups of patients when the response 24 h after the MMSE score and MMSE score before anesthesia,the difference Not statistically significant(P 0.05).Tip of cognitive function in patients with the control group after 6 h,recovered to the level before anesthesia;observation group after 24 h,recovered to the level before anesthesia.Conclusion Propofole intravenous anesthesia and sevoflurane inhalation anesthesia with elderly cancer patients bath can cause short-term cognitive decline and reversible.Patient′s recovery time with seveoflution inhalation anesthesia in cognitive function is longer than with propofole intravenous anesthesia.