Postoperative Short-term Cognitive Function in Elderly Orthopedic Patients Treating with General Anesthesia and Epidural Anesthesia

Objective: To study the postoperative short-term cognitive function of the general anesthesia and epidural anesthesia in elderly patients with the orthopedic disease. Methods: 64 elderly patients March 2010 to May 2013 with general anesthesia were divided into two groups by way of random Numbers, the general anesthesia group(32 cases) were given general anesthesia surgery, epidural anesthesia group(32 cases) were given epidural anesthesia surgery, before and after anesthesia arterial blood pressure and heart rate, the time of open, tube drawing and reply, the MMSE score of postoperative 6, 12, 24, 72 h were contrastively analysis. Results: two groups of age, weight, anesthesia time, education time, blood loss, such as general clinical data had no obvious difference(P0.05); before anesthesia, after anesthesia preoperative, 0.5 h and surgery at the end of the arterial blood pressure and heart rate of two groups had significant difference(P0.05); General anesthesia group open and tube drawing and response time, respectively were(30.3 ±10.5) min and(30.3-7.8) min and(33.2 ±9.6 min). Epidural anesthesia group open and tube drawing and response time(30.6 ±11.6) min, respectively(30.1±6.6) min and(34.3 ±8.5) min, there were no significant differences between the two groups(P0.05). General anesthesia group of MMSE score before anesthesia was 29.2 ±1.5, anesthesia and epidural anesthesia group before the MMSE score was 29.1±1.0, with no significant difference(P0.05). After anesthesia, the two groups after the MMSE score of all appear to reduce the change of the recovery, 24 h after anesthesia epidural anesthesia group was significantly better than the MMSE score of 28.7±1.0 of the general anesthesia group 27.3 ±0.8(t=5.491, P=0.000 0.05); 6 h after anesthesia and general anesthesia group 12 hpocd incidence were significantly higher than that of epidural anesthesia group(P0.05), and two groups began to the incidence of POCD in 24 h after anesthesia had no obvious difference(P0.05). Conclusion: The effect of general anesthesia on postoperative short-term cognitive function in elderly patients with orthopaedic surgery significantly is greater than epidural anesthesia.