Comparison on the Blood Glucose Fluctuation of Three Combination Therapy Scheme of Insulin Aspart 30 for Patients with Type 2 Diabetes

Objective: To compare the blood glucose fluctuation of three combination therapy scheme of insulin aspart 30 in type 2 diabetes subjects.Methods: The subjects with type 2 diabetes were divided into 3 groups randomly.Group A: insulin aspart 30 injection,twice daily,plus metformin tablets;Group B: insulin aspart 30 injection,three times daily,plus metformin tablets;Group C: insulin aspart 30 injection,twice daily,plus metformin and acabose tablets.The efficacy and safety economic data were collected and analyzed.Results: The blood glucose of three groups all dropped obviously,and the efficacy and safety were similar in 3 groups.There is no significant diference among three groups,but there were obvious differences among three groups in SDBG,B groupC groupA group,(F=6.02,P0.01);blood glucose before supper of group A showed highest,(7.14±1.06mmol/L,F=5.63,P0.05).Conclusion: The blood glucose fluctuation of scheme B showed least.Scheme A showed poorer control of the blood glucose before supper,compared with scheme B and C.Scheme C showed the shortest time to decrease blood glucose in early-stage.