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2010•The Journal of Clinical PsychiatryRequires access

Comparative study of mirtazapine and venlafaxine in the treatment of depression

Gao Yue-xia

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Abstract

Objective: compare the efficacy and safety of mirtazapine and venlafaxine in the treatment of first-onset depression. Method: 66 patients with first-onset depression were randomly assigned two groups each of which received mirtazapine(n = 32) or venlafaxine treatment(n = 34) for 8 weeks. Hamilton depression rating scale (HAMD) and treatment emergent symptoms scale were used to assess efficacy and side effects. Results: The two groups showed high curative effect rate after the treatment,but no significant difference was found between the two groups. Conclusion: mirtazapine and venlafaxine can be applied as first-line drugs in treatment of depression.

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What this paper is about

Objective: compare the efficacy and safety of mirtazapine and venlafaxine in the treatment of first-onset depression. Method: 66 patients with first-onset depression were randomly assigned two groups each of which received mirtazapine(n = 32) or venlafaxine treatment(n = 34) for 8 weeks. Hamilton depression rating scale (HAMD) and treatment emergent symptoms scale were used to assess efficacy and side effects. Results: The two groups showed high curative effect rate after the treatment,but no significant difference was found between the two groups. Conclusion: mirtazapine and venlafaxine can be applied as first-line drugs in treatment of depression.

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Available abstract

Objective: compare the efficacy and safety of mirtazapine and venlafaxine in the treatment of first-onset depression. Method: 66 patients with first-onset depression were randomly assigned two groups each of which received mirtazapine(n = 32) or venlafaxine treatment(n = 34) for 8 weeks. Hamilton depression rating scale (HAMD) and treatment emergent symptoms scale were used to assess efficacy and side effects. Results: The two groups showed high curative effect rate after the treatment,but no significant difference was found between the two groups. Conclusion: mirtazapine and venlafaxine can be applied as first-line drugs in treatment of depression.

Key concepts: Mirtazapine, Venlafaxine, Hamd, Depression (economics), Rating scale, Medicine, Hamilton depression scale, Venlafaxine Hydrochloride

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