2002•Journal of Clinical CardiologyRequires access

The predictive value of various lipid lipoprotein and bilirubin combinations for prediction of coronary heart disease

Du Rong

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Abstract

Objective:To study the significance of composite index of the serum bilirubin and serum lipid variables in predicting coronary heart disease rk.Methods:A total of 154 patients who had undergone coronary angiography entered the study. Their results of coronary angiography were investigated and they were divided into three groups: ① severe stenochoria ②middle stenochoria ③normal. Serum bilirubin, the traditional risk factors of cholesterol(TC), high density lipoprotein cholesterol(HDL C), Low density lipoprotein cholesterol(LDL C), triglycerides(TG) were tested by discriminant analysis as were TC/HDL C, LDL C/HDL C, TC/(HDL C+bilirubin) and LDL C/(HDL C+bilirubin).Results:Each of these bilirubin containing ratios was found to be an independent risk predictor when tested with the traditional risk factors. When the LDL C/(HDL C+bilirubin) ratio was included with the traditional risk predictors, it elevated the rate of overall correct Conformity of CHD from 44.7 % to 58.6 %.Conclusion:Serum bilirubin can be combined with LDL C/HDL C ratio, TC/HDL C ratios to improved the prediction of CHD.

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Objective:To study the significance of composite index of the serum bilirubin and serum lipid variables in predicting coronary heart disease rk.Methods:A total of 154 patients who had undergone coronary angiography entered the study. Their results of coronary angiography were investigated and they were divided into three groups: ① severe stenochoria ②middle stenochoria ③normal. Serum bilirubin, the traditional risk factors of cholesterol(TC), high density lipoprotein cholesterol(HDL C), Low density lipoprotein cholesterol(LDL C), triglycerides(TG) were tested by discriminant analysis as were TC/HDL C, LDL C/HDL C, TC/(HDL C+bilirubin) and LDL C/(HDL C+bilirubin).Results:Each of these bilirubin containing ratios was found to be an independent risk predictor when tested with the traditional risk factors. When the LDL C/(HDL C+bilirubin) ratio was included with the traditional risk predictors, it elevated the rate of overall correct Conformity of CHD from 44.7 % to 58.6 %.Conclusion:Serum bilirubin can be combined with LDL C/HDL C ratio, TC/HDL C ratios to improved the prediction of CHD.

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Available abstract

Objective:To study the significance of composite index of the serum bilirubin and serum lipid variables in predicting coronary heart disease rk.Methods:A total of 154 patients who had undergone coronary angiography entered the study. Their results of coronary angiography were investigated and they were divided into three groups: ① severe stenochoria ②middle stenochoria ③normal. Serum bilirubin, the traditional risk factors of cholesterol(TC), high density lipoprotein cholesterol(HDL C), Low density lipoprotein cholesterol(LDL C), triglycerides(TG) were tested by discriminant analysis as were TC/HDL C, LDL C/HDL C, TC/(HDL C+bilirubin) and LDL C/(HDL C+bilirubin).Results:Each of these bilirubin containing ratios was found to be an independent risk predictor when tested with the traditional risk factors. When the LDL C/(HDL C+bilirubin) ratio was included with the traditional risk predictors, it elevated the rate of overall correct Conformity of CHD from 44.7 % to 58.6 %.Conclusion:Serum bilirubin can be combined with LDL C/HDL C ratio, TC/HDL C ratios to improved the prediction of CHD.

Key concepts: Medicine, Bilirubin, Internal medicine, Cholesterol, Serum bilirubin, High-density lipoprotein, Risk factor, Cardiology

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