Annual reports:analysis of ADR in Shizuishan hospital in 2008

Objective To analyze the characterstics and regularity of the adverse drug resction(ADR) occurred in our hospital so as to promote rational drug use.Methods By a retrospective study,a total of 118 ADR case reports collected from our hospital from Jan.to Dec.in 2008 were subjected to a statistical analysis in respect of patients' age and sex.Results Of the total 118ADR case reports,69.5% were induced by intravenous administration and 47.5%were induced by anti-infective drugs,followed by drugs used for nervous system and cardiovascular disease.Quinolones were the major anti-infective drugs,which caused ADR in 19 cases(33.9%),of all the quinolones used,levofloxacin took the lead.And the ADRs manifested dominantly by skin rash and pruritus followed by lesions of digestive system and circulatory system.Conclusion ADR monitoring should be strengthened and the related ARD reporting and analying system should be improved to ensure clinical safe,effective and rational use of drugs.