Optimization of the extraction technique for hesperidin in Fructus Aurantilii Immaturus by ultrasonic extraction

Purpose To explore an optimum extraction technique of hesperidin in Fructus Aurantilii Immaturus.Methods The L9(34)orthogonal experimental design using the content of hesperidin as the observation index was used to optimize the conditions of the extraction technique.Results The conditions of the extrating hesperidin in Fructus Aurantilii Immaturus was 95% and 8 fold solvent methanol,3 times of ultrasonic extraction,and 20 min every time.Conclusion The optimal extraction technique of hesperidin in Fructus Aurantii Immaturus was stable and had high extraction rate.It was suitable for extraction of hesperidin from Fructus Aurantilii Immaturus.