2010•Chinese Journal of PharmacovigilanceRequires access

Analysis of 86 Reports of Drug-induced Anaphylactic Shock

Fan Wei

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Abstract

Objective To analyze the general regularity and rescue measures of the drug-induced anaphylactic shock,provide references for clinical reasonable use of medicine.Methods 86 reports of anaphylactic shock were analyzed retrospectively in Jinan adverse drug reaction mornitoring center from 2007 to 2008.Results Anti-microbial drugs and Traditional Chinese Medicine injections were the top two position.The highest incidence of intravenous drug,accounting for 95.35%.The majority of anaphylactic shock occurred within 5 minutes after administration,accounting for 39.53%.Mainly involve and damage included circulation,central nervous,respiratory and systemic.Conclusion The clinical should pay attention to drug-induced anaphylactic shock,strict indications medication,strengthen the guardianship medication.

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Objective To analyze the general regularity and rescue measures of the drug-induced anaphylactic shock,provide references for clinical reasonable use of medicine.Methods 86 reports of anaphylactic shock were analyzed retrospectively in Jinan adverse drug reaction mornitoring center from 2007 to 2008.Results Anti-microbial drugs and Traditional Chinese Medicine injections were the top two position.The highest incidence of intravenous drug,accounting for 95.35%.The majority of anaphylactic shock occurred within 5 minutes after administration,accounting for 39.53%.Mainly involve and damage included circulation,central nervous,respiratory and systemic.Conclusion The clinical should pay attention to drug-induced anaphylactic shock,strict indications medication,strengthen the guardianship medication.

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Available abstract

Objective To analyze the general regularity and rescue measures of the drug-induced anaphylactic shock,provide references for clinical reasonable use of medicine.Methods 86 reports of anaphylactic shock were analyzed retrospectively in Jinan adverse drug reaction mornitoring center from 2007 to 2008.Results Anti-microbial drugs and Traditional Chinese Medicine injections were the top two position.The highest incidence of intravenous drug,accounting for 95.35%.The majority of anaphylactic shock occurred within 5 minutes after administration,accounting for 39.53%.Mainly involve and damage included circulation,central nervous,respiratory and systemic.Conclusion The clinical should pay attention to drug-induced anaphylactic shock,strict indications medication,strengthen the guardianship medication.

Key concepts: Anaphylactic shock, Medicine, Drug, Shock (circulatory), Anesthesia, Adverse drug reaction, Incidence (geometry), Intensive care medicine

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