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2011•Chinese and Foreign Medical ResearchRequires access

Diagnostic value of combined detection in serum tumor makers for hung cancer

WU Chuan-q

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Abstract

Objective To explore the Diagnostic value of combined detection in serum NSE,CYFRA21-1 and CA19-9 levels for hung cancer.Methods Technique of electrochemiluminescence immunoassay was used to measure the serum NSE,CYFRA21-1 and CA19-9 levels in 112 patients with lung cancer,68 patients with benige lung diseases and 50 normal controls.Results The levels of NSE,CYFRA21-1 and CA19-9 in lung cancer group were significantly higher than those in benign lung diseases and normal control groups(P0.01).Three tumor markers positive rate as high as 82.1%,accuracy was 90.0%,higher than the single test.Conclusion Three tumor markers of combined detection for lung cancer can improve the sensitivity and accuracy.

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What this paper is about

Objective To explore the Diagnostic value of combined detection in serum NSE,CYFRA21-1 and CA19-9 levels for hung cancer.Methods Technique of electrochemiluminescence immunoassay was used to measure the serum NSE,CYFRA21-1 and CA19-9 levels in 112 patients with lung cancer,68 patients with benige lung diseases and 50 normal controls.Results The levels of NSE,CYFRA21-1 and CA19-9 in lung cancer group were significantly higher than those in benign lung diseases and normal control groups(P0.01).Three tumor markers positive rate as high as 82.1%,accuracy was 90.0%,higher than the single test.Conclusion Three tumor markers of combined detection for lung cancer can improve the sensitivity and accuracy.

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Available abstract

Objective To explore the Diagnostic value of combined detection in serum NSE,CYFRA21-1 and CA19-9 levels for hung cancer.Methods Technique of electrochemiluminescence immunoassay was used to measure the serum NSE,CYFRA21-1 and CA19-9 levels in 112 patients with lung cancer,68 patients with benige lung diseases and 50 normal controls.Results The levels of NSE,CYFRA21-1 and CA19-9 in lung cancer group were significantly higher than those in benign lung diseases and normal control groups(P0.01).Three tumor markers positive rate as high as 82.1%,accuracy was 90.0%,higher than the single test.Conclusion Three tumor markers of combined detection for lung cancer can improve the sensitivity and accuracy.

Key concepts: Medicine, Lung cancer, Internal medicine, Tumor marker, Immunoassay, Cancer, Lung, Gastroenterology

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