Extraction of Total Alkaloids from Mixed Herbs Yisuitongjing

The extraction method and process for total alkaloids in a herb mixture named Yisuitongjing were optimized in this paper.With the content of total alkaloids as indexes,the extraction method was optimized by single factor experiment and the extraction process was optimized by orthogonal experiment.The highest extraction yield of total alkaloids were reached when using ethanol as reflux extraction regent and adding 50% ethanol solution for twelve times with extracting time 2.0 h.The extraction process was simple and reasonable,suitable for industrial production.