Clinical observation of amiodarone combined with benazepril in treatment of paroxysmal atrial fibrillation

Objective To discuss the clinical effect of amiodarone combined with benazepril in the treatment of paroxysmal atrial fibrillation.Methods 63 cases of patients with paroxysmal atrial fibrillation were randomly divided into study group of 33 cases and control group of 30 cases.The control group was given amiodarone on the basis of treating the primary diseases and anticoagulant therapy.The study group was given benazepril on the basis of the control group.Both groups were followed up 12 months.The clinical effect and left atrial diameter(LAD)before and after the treatment of 2 groups were compared.Results The total effective rates of the study group(93.9%) was higher than that of the control group(76.6%);after treatment,the LAD of the study group was shorter than before treatment and shorter than that of the control group,and the differences were statistically significant(P0.05).Conclusion The clinical effect of amiodarone combined with benazepril in the treatment of paroxysmal atrial fibrillation was better than that of amiodarone,It is effective to prevent the recurrence of atrial fibrillation and the occurrence of persistent atrial fibrillation by using amiodarone combined with benazepril,which can shorten the LAD significantly and delay the enlargement of left atrium significantly.