Observation of the efficacy of combined telmisartan and amiodarone use in treatment of paroxysmal atrial fibrillation

Objective To observe the efficacy of combined telmisartan and amiodarone use on treatment of paroxysmal atrial fibrillation.Methods Patients were randomly divided into amiodarone group(A,n=32) and amiodarone plus telmisartan group(AT,n=32) and all patients received conventional therapy.Results Two years post therapy,episodes of atrial fibrillation frequency reduced obviously and atrial fibrillation duration shortened.Atrial fibrillation episodes reduced amplitude in group AT was obviously higher than that of group A(P 0.05),observation of left atrial diameter with the extension of time and expands,left atrial diameter average increase of the group AT was significantly smaller than that of the group A after treatment(P 0.01).Conclusion Combined telmisartan and amiodarone use is more effective in preventing paroxysmal atrial fibrillation recurrence,they both can better inhibit atrial remodeling and delay atrial enlargement,whose efficacy is obviously superior to amiodarone alone.