Application Value of ~(18)F-FDG PET/ CT in Ovarian Cancer

Objective To evaluate the value of PET/CT in preoperative assessment and postoperative monitoring of ovarian cancer. Methods A retrospective analysis was conducted in 45 patients of ovarian neoplasm with clinical records underwent18F-FDG PET/CT, including 10 patients underwent PET/CT before surgery and 35patients after surgery. The clinical follow-up time was 6 months at least. The diagnosis based on pathology and clinical follow-up data. Results(1) The sensitivity, specificity and accuracy of PET/CT in detecting ovarian cancer were94.6%,75.0% and 91.1%, respectively.(2) Ten patients before surgery were all detected tumor by PET/CT,but 2 of them were false positive based on pathologic results.(3) Two patients with non-standard surgery were detected tumor by PET/CT. In 33 patients after standard surgery, 6 patients were no tumor detected by PET/CT. In addition,4 patients with normal CA125 and no signs of recurrence and metastasis were detected tumor by PET/CT.The pathology and clinical follow-up data supported the results. 23 patients with higher CA125 were diagnosed recurrence and metastasis based on pathology and clinical follow-up data,21 of them were detected tumor by PET/CT. Conclusion18F-FDG PET/CT plays an important role in preoperative assessment, early diagnosis and accurate positioning of recurrent and metastasis of ovarian cancer. It can be used to guide the clinical treatment.