Value of ~(18)F-FDG PET/CT in Follow-up of Ovarian Cancer Patients after Therapy

Purpose:To evaluate the use of ~(18)F-PET/CT in follow-up of ovarian cancer patients after therapy.Methods:A retrospective study was performed on 152 ovarian cancer patients after therapy.The following information was collected and analyzed:clinical material,CA125 and traditional imaging result. According to the indication for PET/CT,the patients were divided into 5 groups.The role of ~(18)F-PET/CT in evaluation of surveillance and clinical management of ovarian cancer patients after therapy compared with the result of clinical follow-up was analyzed.Results:Of 137 patients with follow-up results,105 patients were diagnosed as recurrence and 32 as disease free after long duration follow-up.The diagnostic sensitivity, specificity,accuracy,positive predictive value,negative predictive value were 98.3%,91.2%,96.8%,97.5%, 93.9%,respectively.PET/CT was especially useful for the correct clinical therapeutic decision making for the patients whose PET/CT indications were to diagnose suspected recurrence,for the assessment of disease extent and for the evaluation of therapeutic response.Conclusion:PET/CT has extremely high diagnostic value for recurrent ovarian cancer and is specifically helpful in optimizing the selection of patients for appropriate treatment.