Association of HbAlc and coronary heart disease in the different glucose metabolic states

Objective:To investigate the association of glycated hemoglobin(HbAlc) and coronary heart disease in the different glucose metabolic states.Methods: A total of 644 hospitalized patients with suspicious coronary heart disease was selected in Anzhen hospital.Clinical data have been collected,HbA1c concentrations,fasting glucose(FBG),postload glucose(PPG),were measured.Coronary angiography was performed in all patients.According to the results of CAG,the 644 patients were divided into two groups: CHD group and non-CHD group as control.Results: HbA1c concentrations in the patients of the CHD group were significantly higher than that in the patients of the control group.HbA1c concentrations increased with the increasing number of diseased coronary branches.The incidence of CHD increases with the rise of HbA1c level.Conclusion: 1.In NGT group,HbA1c may also be associated with the occurrence of coronary heart disease.2.HbA1c ≥ 5.6%,coronary heart disease incidence of non diabetic patients may be significantly elevated.