Clinic analysis of 4809 cases of gestational glucose challenge test screen.

Objective To study the clinic value of the 50 gram glucose challenge test(GCT) to screen the gestational diabetes mellitua(GDM) in different pregnant weeks,and the relationships of maternal age,body weight and pregnant weeks to GDM.Methods The clinical data of 4809 pregnant women who underwent the GCT from Januuary 2006 to March 2009 in Perinatal Healthcare department of our hospital were collected,All women were divided into three groups :(A group)less than 24 weeks of gestation group,(B group) 24～28 weeks of gestation group and(C group) more than 28 weeks of gestation group.75 gram glucose tolerance test(OGTT) were performed in all the women who were positive in GCT and they were divided into three groups:normal group,Glucose intolerance(GIGT) group;GDM group.A control study were made based on pregnant women′s age and weight.Rerults ①We compared A,B and C group,there were no significant difference in the abnormal rate of GCT and GDM(P0.05).②There were significant difference of the abnormal rate of GCT and GDM when compared by pregnant women′s age and weight(P0.05).The incidence rate of GDM of pregnant women younger than 25 years old without high risk factors was significantly lower than women older than 25 years.The incidence rate of GCT and GDM of pregnant women whose BMI were on less than 25.1 were significantly higher than that of BMI lower than 25.1.Conclusions ①It is suitable to screen GDM during gestation not only for 24 to 28 weeks.②Age and weight of pregnant women are the important risk factors for the GDM.It is necessary to screen GDM as soon as possible for pregnant women with obesity or older age.