Preliminary Analysis of Western Guangdong Women with Genital HPV Infection and CIN and Cervical Cancer

Objective:To understand western Guangdong women with genital HPV(human papilloma virus,HPV) infection,or high risk HPV infection and cervical intraepithelial neoplasia(cervical intraepithelial neoplasia,CIN) and cervical cancer.Methods:With PCR-reverse dot blot method,maternal and child health doctors in Zhanjiang City collected 296 cases of gynecological outpatient and inpatient married women aged 20 to 55,or unmarried sexually active women in cervical secretions in 15 types of HPV genotypes: 13 species High-risk HPV(16、18、31、33、35、39、45、51、52、56、58、59、68)and low-risk type 2(6、11).Results:In 296 cases of cervical secretion,114 cases were found positive,the total positive rate was 38.5%.The groups of normal,CIN and cervical cancer HPV infection were 16.4%,63.4% and 84.2%;high-risk type HPV infection was significantly higher than the low-risk type(P0.01);infection peak in 25 ～ 45 years age group;general population HPV-16 had highest rates of infection.Conclusion:Female genital HPV infection is a high risk of cervical cancer and CIN of popular western Guangdong women,the main factor for cervical cancer should be prevention of HPV infection,HPV infection screening and close monitoring of high risk HPV are very important to infected object.HPV testing is a practical means of cervical cancer screening.